The detection of malignant melanoma by bone marrow aspiration; a report of two cases.

RADCLIFFE, M.D. S INCE 1936, when Rohr and Hegglin’ first recognized tumor cells in the bone marrow, numerous arti(les have appeared reporting bone marrow metastases in neuroblastomas, sarcomas and a wide variety of carcinomas including tumors of the prostate, breast, lung, stomach, colon, kidney, other organs and undetermined primary sites. The value of sternal and iliac marrow aspirations as diagnostic and prognostic aids has been emphasized by many investigators, yet there is little information recorded on melanoma cells in the marrow. A search of the literature revealed only 8 cases, to which we are recording 2 additional cases.